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Decoding the Therapeutic Implications of the ERα Stability and Subcellular Distribution in Breast Cancer

Approximately 70% of all breast cancer cases are estrogen receptor-alpha positive (ERα+) and any ERα signaling pathways deregulation is critical for the progression of malignant mammary neoplasia. ERα acts as a transcription factor that promotes the expression of estrogen target genes associated wit...

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Detalles Bibliográficos
Autores principales: Tecalco-Cruz, Angeles C., Macías-Silva, Marina, Ramírez-Jarquín, Josué Orlando, Ramírez-Jarquín, Uri Nimrod
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044904/
https://www.ncbi.nlm.nih.gov/pubmed/35498431
http://dx.doi.org/10.3389/fendo.2022.867448