Candida auris Bloodstream Infection Induces Upregulation of the PD-1/PD-L1 Immune Checkpoint Pathway in an Immunocompetent Mouse Model

Candida auris is a globally spreading yeast pathogen causing bloodstream infections with high mortality in critically ill patients. The inherent antifungal drug resistance of most C. auris isolates and threat of multidrug-resistant strains create a need for adjunct immunotherapeutic strategies. Whil...

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Detalles Bibliográficos
Autores principales: Wurster, Sebastian, Albert, Nathaniel D., Kontoyiannis, Dimitrios P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Observation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044930/
https://www.ncbi.nlm.nih.gov/pubmed/35224979
http://dx.doi.org/10.1128/msphere.00817-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044930/
https://www.ncbi.nlm.nih.gov/pubmed/35224979
http://dx.doi.org/10.1128/msphere.00817-21

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