SARS-CoV-2 nsp5 Exhibits Stronger Catalytic Activity and Interferon Antagonism than Its SARS-CoV Ortholog

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to pose an enormous threat to economic activity and public health worldwide. Previous studies have shown that the nonstructural protein 5 (nsp5, also called 3C-like protease) of alpha- and deltacoronaviruses cleaves Q231 of the N...

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Detalles Bibliográficos
Autores principales: Chen, Jiyao, Li, Zhuang, Guo, Jiahui, Xu, Shangen, Zhou, Junwei, Chen, Qian, Tong, Xue, Wang, Dang, Peng, Guiqing, Fang, Liurong, Xiao, Shaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Virus-Cell Interactions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044939/
https://www.ncbi.nlm.nih.gov/pubmed/35389264
http://dx.doi.org/10.1128/jvi.00037-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044939/
https://www.ncbi.nlm.nih.gov/pubmed/35389264
http://dx.doi.org/10.1128/jvi.00037-22

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