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Control of Variant Surface Glycoprotein Expression by CFB2 in Trypanosoma brucei and Quantitative Proteomic Connections to Translation and Cytokinesis

Variant surface glycoproteins (VSGs) coat parasitic African trypanosomes and underpin antigenic variation and immune evasion. These VSGs are superabundant virulence factors that are subject to posttranscriptional gene expression controls mediated via the VSG 3′ untranslated region (UTR). To identify...

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Detalles Bibliográficos
Autores principales: Bravo Ruiz, Gustavo, Tinti, Michele, Ridgway, Melanie, Horn, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044945/
https://www.ncbi.nlm.nih.gov/pubmed/35306877
http://dx.doi.org/10.1128/msphere.00069-22