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The In Vivo and In Vitro Architecture of the Hepatitis C Virus RNA Genome Uncovers Functional RNA Secondary and Tertiary Structures

Hepatitis C virus (HCV) is a positive-strand RNA virus that remains one of the main contributors to chronic liver disease worldwide. Studies over the last 30 years have demonstrated that HCV contains a highly structured RNA genome and many of these structures play essential roles in the HCV life cyc...

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Detalles Bibliográficos
Autores principales: Wan, Han, Adams, Rebecca L., Lindenbach, Brett D., Pyle, Anna Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044954/
https://www.ncbi.nlm.nih.gov/pubmed/35353000
http://dx.doi.org/10.1128/jvi.01946-21