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Synergistic Antibiofilm Effects of Pseudolaric Acid A Combined with Fluconazole against Candida albicans via Inhibition of Adhesion and Yeast-To-Hypha Transition

Candida albicans biofilms are resistant to several clinical antifungal agents. Thus, it is necessary to develop new antibiofilm intervention measures. Pseudolaric acid A (PAA), a diterpenoid mainly derived from the pine bark of Pseudolarix kaempferi, has been reported to have an inhibitory effect on...

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Detalles Bibliográficos
Autores principales: Zhu, Bin, Li, Zhen, Yin, Hongmei, Hu, Jun, Xue, Yingjun, Zhang, Guanyi, Zheng, Xin, Chen, Weiqin, Hu, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045105/
https://www.ncbi.nlm.nih.gov/pubmed/35297651
http://dx.doi.org/10.1128/spectrum.01478-21