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Proteomic Response Revealed Signaling Pathways Involving in the Mechanism of Polymyxin B-Induced Melanogenesis

Polymyxin B is a last-line antibiotic for extensively resistant Gram-negative bacterial infection. Skin hyperpigmentation is a serious side effect induced by polymyxin B that severely compromises the psychological health and compliance of patients. The literature lacks mechanistic studies that expla...

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Detalles Bibliográficos
Autores principales: Zhang, Chuhan, Liu, Xiaofen, Wu, Hailan, Wang, Yu, Fan, Yaxin, Guo, Beining, Bian, Xingchen, Li, Xin, Zhang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045165/
https://www.ncbi.nlm.nih.gov/pubmed/35377227
http://dx.doi.org/10.1128/spectrum.02730-21