Development of Antifungal Peptides against Cryptococcus neoformans; Leveraging Knowledge about the cdc50Δ Mutant Susceptibility for Lead Compound Development

Cryptococcus neoformans is a major fungal pathogen that often causes life-threatening meningitis in immunocompromised populations. This yeast pathogen is highly resistant to the echinocandin drug caspofungin. Previous studies showed that Cryptococcus lipid translocase (flippase) is required for the...

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Detalles Bibliográficos
Autores principales: Tancer, Robert J., Wang, Yina, Pawar, Siddhi, Xue, Chaoyang, Wiedman, Gregory R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045296/
https://www.ncbi.nlm.nih.gov/pubmed/35377230
http://dx.doi.org/10.1128/spectrum.00439-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045296/
https://www.ncbi.nlm.nih.gov/pubmed/35377230
http://dx.doi.org/10.1128/spectrum.00439-22

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