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In Silico Drug Discovery Strategies Identified ADMET Properties of Decoquinate RMB041 and Its Potential Drug Targets against Mycobacterium tuberculosis

The highly adaptive cellular response of Mycobacterium tuberculosis to various antibiotics and the high costs for clinical trials, hampers the development of novel antimicrobial agents with improved efficacy and safety. Subsequently, in silico drug screening methods are more commonly being used for...

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Detalles Bibliográficos
Autores principales: Knoll, Kirsten E., van der Walt, Mietha M., Loots, Du Toit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045315/
https://www.ncbi.nlm.nih.gov/pubmed/35352998
http://dx.doi.org/10.1128/spectrum.02315-21