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Profiling of SARS-CoV-2 Subgenomic RNAs in Clinical Specimens

SARS-CoV-2 transcribes a set of subgenomic RNAs (sgRNAs) essential for the translation of structural and accessory proteins to sustain its life cycle. We applied RNA-seq on 375 respiratory samples from individual COVID-19 patients and revealed that the majority of the sgRNAs were canonical transcrip...

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Detalles Bibliográficos
Autores principales: Chen, Zigui, Ng, Rita Way Yin, Lui, Grace, Ling, Lowell, Chow, Chit, Yeung, Apple Chung Man, Boon, Siaw Shi, Wang, Maggie Haitian, Chan, Kate Ching Ching, Chan, Renee Wan Yi, Hui, David Shu Cheong, Chan, Paul Kay Sheung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045320/
https://www.ncbi.nlm.nih.gov/pubmed/35311586
http://dx.doi.org/10.1128/spectrum.00182-22