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Fluconazole Population Pharmacokinetics after Fosfluconazole Administration and Dosing Optimization in Extremely Low-Birth-Weight Infants

A prospective single-center study was conducted to characterize the pharmacokinetics (PK) of fluconazole (FLCZ) in extremely low-birth-weight infants (ELBWIs) who received fosfluconazole (F-FLCZ). Intravenous F-FLCZ was administered at a dose of 3 mg/kg of body weight every 72 h during the first 2 w...

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Detalles Bibliográficos
Autores principales: Tanzawa, Ayano, Saito, Jumpei, Shoji, Kensuke, Kojo, Yuka, Funaki, Takanori, Maruyama, Hidehiko, Isayama, Tetsuya, Ito, Yushi, Nakamura, Hidefumi, Yamatani, Akimasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045325/
https://www.ncbi.nlm.nih.gov/pubmed/35266811
http://dx.doi.org/10.1128/spectrum.01952-21