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Disruption of Iron Homeostasis and Mitochondrial Metabolism Are Promising Targets to Inhibit Candida auris

Fungal infections are a global threat, but treatments are limited due to a paucity in antifungal drug targets and the emergence of drug-resistant fungi such as Candida auris. Metabolic adaptations enable microbial growth in nutrient-scarce host niches, and they further control immune responses to pa...

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Detalles Bibliográficos
Autores principales: Simm, Claudia, Weerasinghe, Harshini, Thomas, David R., Harrison, Paul F., Newton, Hayley J., Beilharz, Traude H., Traven, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045333/
https://www.ncbi.nlm.nih.gov/pubmed/35412372
http://dx.doi.org/10.1128/spectrum.00100-22