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Disruption of Iron Homeostasis and Mitochondrial Metabolism Are Promising Targets to Inhibit Candida auris
Fungal infections are a global threat, but treatments are limited due to a paucity in antifungal drug targets and the emergence of drug-resistant fungi such as Candida auris. Metabolic adaptations enable microbial growth in nutrient-scarce host niches, and they further control immune responses to pa...
Autores principales: | Simm, Claudia, Weerasinghe, Harshini, Thomas, David R., Harrison, Paul F., Newton, Hayley J., Beilharz, Traude H., Traven, Ana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045333/ https://www.ncbi.nlm.nih.gov/pubmed/35412372 http://dx.doi.org/10.1128/spectrum.00100-22 |
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