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A Novel Antimicrobial Peptide Derived from Bony Fish IFN1 Exerts Potent Antimicrobial and Anti-Inflammatory Activity in Mammals

Type I interferons (IFN-Is) are critical antiviral cytokine in innate immunity but with limited direct defense ability against bacterial infections in mammals. In bony fish, despite all the IFN-Is (IFN1-4) act in antiviral immunity, studies demonstrate that IFN1 can remarkably contribute to host def...

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Detalles Bibliográficos
Autores principales: Xiao, Xun, Lu, Hao, Zhu, Wentao, Zhang, Yanqi, Huo, Xingchen, Yang, Chunrong, Xiao, Shaobo, Zhang, Yongan, Su, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045357/
https://www.ncbi.nlm.nih.gov/pubmed/35289673
http://dx.doi.org/10.1128/spectrum.02013-21