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Discovery and Characterization of an Aberrant Small Form of Glycoprotein I of Herpes Simplex Virus Type I in Cell Culture

The 380-to-393-amino-acid glycoprotein I (gI) encoded by herpes simplex virus 1 (HSV-1) is a critical mediator for viral cell-to-cell spread and syncytium formation. Here we report a previously unrecognized aberrant form of gI in HSV-1-infected cells. Production of this molecule is independent of ce...

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Detalles Bibliográficos
Autores principales: Gui, Xixi, Zhang, Wuchao, Gao, Peng, Zhang, Yongning, Zhou, Lei, Ge, Xinna, Guo, Xin, Wills, John W., Han, Jun, Yang, Hanchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045375/
https://www.ncbi.nlm.nih.gov/pubmed/35348373
http://dx.doi.org/10.1128/spectrum.02659-21