Mycobacterium tuberculosis PknK Substrate Profiling Reveals Essential Transcription Terminator Protein Rho and Two-Component Response Regulators PrrA and MtrA as Novel Targets for Phosphorylation

The Mycobacterium tuberculosis protein kinase K regulates growth adaptation by facilitating mycobacterial survival in response to a variety of in vitro and in vivo stress conditions. Here, we further add that pknK transcription is responsive to carbon and nitrogen starvation signals. The increased s...

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Detalles Bibliográficos
Autores principales: Malhotra, Vandana, Okon, Blessing P., Satsangi, Akash T., Das, Sumana, Waturuocha, Uchenna Watson, Vashist, Atul, Clark-Curtiss, Josephine E., Saini, Deepak Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045387/
https://www.ncbi.nlm.nih.gov/pubmed/35404097
http://dx.doi.org/10.1128/spectrum.01354-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045387/
https://www.ncbi.nlm.nih.gov/pubmed/35404097
http://dx.doi.org/10.1128/spectrum.01354-21

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