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Mycobacterium tuberculosis PknK Substrate Profiling Reveals Essential Transcription Terminator Protein Rho and Two-Component Response Regulators PrrA and MtrA as Novel Targets for Phosphorylation
The Mycobacterium tuberculosis protein kinase K regulates growth adaptation by facilitating mycobacterial survival in response to a variety of in vitro and in vivo stress conditions. Here, we further add that pknK transcription is responsive to carbon and nitrogen starvation signals. The increased s...
Autores principales: | Malhotra, Vandana, Okon, Blessing P., Satsangi, Akash T., Das, Sumana, Waturuocha, Uchenna Watson, Vashist, Atul, Clark-Curtiss, Josephine E., Saini, Deepak Kumar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045387/ https://www.ncbi.nlm.nih.gov/pubmed/35404097 http://dx.doi.org/10.1128/spectrum.01354-21 |
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