atpE Mutation in Mycobacterium tuberculosis Not Always Predictive of Bedaquiline Treatment Failure

We report the emergence of an atpE mutation in a clinical Mycobacterium tuberculosis strain. Genotypic and phenotypic bedaquiline susceptibility testing displayed variable results over time and ultimately were not predictive of treatment outcome. This observation highlights the limits of current gen...

Descripción completa

Detalles Bibliográficos
Autores principales: Le Ray, Laure Fournier, Aubry, Alexandra, Sougakoff, Wladimir, Revest, Matthieu, Robert, Jérôme, Bonnet, Isabelle, Veziris, Nicolas, Morel, Florence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2022
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045433/
https://www.ncbi.nlm.nih.gov/pubmed/35447056
http://dx.doi.org/10.3201/eid2805.212517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045433/
https://www.ncbi.nlm.nih.gov/pubmed/35447056
http://dx.doi.org/10.3201/eid2805.212517

Ejemplares similares