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Mycobacterium tuberculosis requires SufT for Fe-S cluster maturation, metabolism, and survival in vivo

Iron-sulfur (Fe-S) cluster proteins carry out essential cellular functions in diverse organisms, including the human pathogen Mycobacterium tuberculosis (Mtb). The mechanisms underlying Fe-S cluster biogenesis are poorly defined in Mtb. Here, we show that Mtb SufT (Rv1466), a DUF59 domain-containing...

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Detalles Bibliográficos
Autores principales: Tripathi, Ashutosh, Anand, Kushi, Das, Mayashree, O’Niel, Ruchika Annie, P. S, Sabarinath, Thakur, Chandrani, R. L., Raghunatha Reddy, Rajmani, Raju S., Chandra, Nagasuma, Laxman, Sunil, Singh, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045647/
https://www.ncbi.nlm.nih.gov/pubmed/35427399
http://dx.doi.org/10.1371/journal.ppat.1010475