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Inheritance of repressed chromatin domains during S phase requires the histone chaperone NPM1

The epigenetic process safeguards cell identity during cell division through the inheritance of appropriate gene expression profiles. We demonstrated previously that parental nucleosomes are inherited by the same chromatin domains during DNA replication only in the case of repressed chromatin. We no...

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Detalles Bibliográficos
Autores principales: Escobar, Thelma M., Yu, Jia-Ray, Liu, Sanxiong, Lucero, Kimberly, Vasilyev, Nikita, Nudler, Evgeny, Reinberg, Danny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045712/
https://www.ncbi.nlm.nih.gov/pubmed/35476441
http://dx.doi.org/10.1126/sciadv.abm3945