The immune checkpoint B7-H3 (CD276) regulates adipocyte progenitor metabolism and obesity development

The immune checkpoint B7-H3 (CD276) is a member of the B7 family that has been studied in the tumor microenvironment and immunotherapy, but its potential role in metabolism remains largely unknown. Here, we show that B7-H3 is highly expressed in mouse and human adipose tissue at steady state, with t...

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Detalles Bibliográficos
Autores principales: Picarda, Elodie, Galbo, Phillip M., Zong, Haihong, Rajan, Meenu Rohini, Wallenius, Ville, Zheng, Deyou, Börgeson, Emma, Singh, Rajat, Pessin, Jeffrey, Zang, Xingxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045715/
https://www.ncbi.nlm.nih.gov/pubmed/35476450
http://dx.doi.org/10.1126/sciadv.abm7012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045715/
https://www.ncbi.nlm.nih.gov/pubmed/35476450
http://dx.doi.org/10.1126/sciadv.abm7012

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