Concerted modification of nucleotides at functional centers of the ribosome revealed by single-molecule RNA modification profiling

Nucleotides in RNA and DNA are chemically modified by numerous enzymes that alter their function. Eukaryotic ribosomal RNA (rRNA) is modified at more than 100 locations, particularly at highly conserved and functionally important nucleotides. During ribosome biogenesis, modifications are added at va...

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Detalles Bibliográficos
Autores principales: Bailey, Andrew D, Talkish, Jason, Ding, Hongxu, Igel, Haller, Duran, Alejandra, Mantripragada, Shreya, Paten, Benedict, Ares, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045821/
https://www.ncbi.nlm.nih.gov/pubmed/35384842
http://dx.doi.org/10.7554/eLife.76562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045821/
https://www.ncbi.nlm.nih.gov/pubmed/35384842
http://dx.doi.org/10.7554/eLife.76562

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