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Evidence showing lipotoxicity worsens outcomes in covid-19 patients and insights about the underlying mechanisms

We compared three hospitalized patient cohorts and conducted mechanistic studies to determine if lipotoxicity worsens COVID-19. Cohort-1 (n = 30) compared COVID-19 patients dismissed home to those requiring intensive-care unit (ICU) transfer. Cohort-2 (n = 116) compared critically ill ICU patients w...

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Detalles Bibliográficos
Autores principales: Cartin-Ceba, Rodrigo, Khatua, Biswajit, El-Kurdi, Bara, Trivedi, Shubham, Kostenko, Sergiy, Imam, Zaid, Smith, Ryan, Snozek, Christine, Navina, Sarah, Sharma, Vijeta, McFayden, Bryce, Ionescu, Filip, Stolow, Eugene, Keiser, Sylvia, Tejani, Aziz, Harrington, Allison, Acosta, Phillip, Kuwelker, Saatchi, Echavarria, Juan, Nair, Girish B., Bataineh, Adam, Singh, Vijay P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045865/
https://www.ncbi.nlm.nih.gov/pubmed/35502320
http://dx.doi.org/10.1016/j.isci.2022.104322