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RBD-mRNA vaccine induces broadly neutralizing antibodies against Omicron and multiple other variants and protects mice from SARS-CoV-2 challenge

Multiple SARS-CoV-2 variants are identified with higher rates of transmissibility or greater disease severity. Particularly, recent emergence of Omicron variant with rapid human-to-human transmission posts new challenges to the current prevention strategies. In this study, following vaccination with...

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Detalles Bibliográficos
Autores principales: Shi, Juan, Zheng, Jian, Zhang, Xiujuan, Tai, Wanbo, Odle, Abby E., Perlman, Stanley, Du, Lanying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045870/
https://www.ncbi.nlm.nih.gov/pubmed/35489692
http://dx.doi.org/10.1016/j.trsl.2022.04.007