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Polysaccharides from Polygonatum cyrtonema Hua Reduce Depression-Like Behavior in Mice by Inhibiting Oxidative Stress-Calpain-1-NLRP3 Signaling Axis

Polysaccharides from Polygonatum cyrtonema Hua (PSP) exert antioxidant, anti-inflammatory, and antidepressant effects. Production of reactive oxygen species (ROS) and activation of the calpain system and the NOD-like receptor protein 3 (NLRP3) inflammasome are closely related to the pathogenesis of...

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Detalles Bibliográficos
Autores principales: Shen, Fengming, Xie, Pan, Li, Congting, Bian, Zhijuan, Wang, Xuncui, Peng, Daiyin, Zhu, Guoqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9045988/
https://www.ncbi.nlm.nih.gov/pubmed/35498131
http://dx.doi.org/10.1155/2022/2566917