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Structural basis of tethered agonism of the adhesion GPCRs ADGRD1 and ADGRF1
Adhesion G protein-coupled receptors (aGPCRs) are essential for a variety of physiological processes such as immune responses, organ development, cellular communication, proliferation and homeostasis(1–7). An intrinsic manner of activation that involves a tethered agonist in the N-terminal region of...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046087/ https://www.ncbi.nlm.nih.gov/pubmed/35418679 http://dx.doi.org/10.1038/s41586-022-04580-w |