Cargando…

Structural basis of tethered agonism of the adhesion GPCRs ADGRD1 and ADGRF1

Adhesion G protein-coupled receptors (aGPCRs) are essential for a variety of physiological processes such as immune responses, organ development, cellular communication, proliferation and homeostasis(1–7). An intrinsic manner of activation that involves a tethered agonist in the N-terminal region of...

Descripción completa

Detalles Bibliográficos
Autores principales: Qu, Xiangli, Qiu, Na, Wang, Mu, Zhang, Bingjie, Du, Juan, Zhong, Zhiwei, Xu, Wei, Chu, Xiaojing, Ma, Limin, Yi, Cuiying, Han, Shuo, Shui, Wenqing, Zhao, Qiang, Wu, Beili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046087/
https://www.ncbi.nlm.nih.gov/pubmed/35418679
http://dx.doi.org/10.1038/s41586-022-04580-w