Peptidoglycan biosynthesis is driven by lipid transfer along enzyme-substrate affinity gradients

Maintenance of bacterial cell shape and resistance to osmotic stress by the peptidoglycan (PG) renders PG biosynthetic enzymes and precursors attractive targets for combating bacterial infections. Here, by applying native mass spectrometry, we elucidate the effects of lipid substrates on the PG memb...

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Detalles Bibliográficos
Autores principales: Oluwole, Abraham O., Corey, Robin A., Brown, Chelsea M., Hernández-Rocamora, Victor M., Stansfeld, Phillip J., Vollmer, Waldemar, Bolla, Jani R., Robinson, Carol V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046198/
https://www.ncbi.nlm.nih.gov/pubmed/35477938
http://dx.doi.org/10.1038/s41467-022-29836-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046198/
https://www.ncbi.nlm.nih.gov/pubmed/35477938
http://dx.doi.org/10.1038/s41467-022-29836-x

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