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Peptidoglycan biosynthesis is driven by lipid transfer along enzyme-substrate affinity gradients
Maintenance of bacterial cell shape and resistance to osmotic stress by the peptidoglycan (PG) renders PG biosynthetic enzymes and precursors attractive targets for combating bacterial infections. Here, by applying native mass spectrometry, we elucidate the effects of lipid substrates on the PG memb...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046198/ https://www.ncbi.nlm.nih.gov/pubmed/35477938 http://dx.doi.org/10.1038/s41467-022-29836-x |