Foldamers reveal and validate therapeutic targets associated with toxic α-synuclein self-assembly

Parkinson’s disease (PD) is a progressive neurodegenerative disorder for which there is no successful prevention or intervention. The pathological hallmark for PD involves the self-assembly of functional Alpha-Synuclein (αS) into non-functional amyloid structures. One of the potential therapeutic in...

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Detalles Bibliográficos
Autores principales: Ahmed, Jemil, Fitch, Tessa C., Donnelly, Courtney M., Joseph, Johnson A., Ball, Tyler D., Bassil, Mikaela M., Son, Ahyun, Zhang, Chen, Ledreux, Aurélie, Horowitz, Scott, Qin, Yan, Paredes, Daniel, Kumar, Sunil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046208/
https://www.ncbi.nlm.nih.gov/pubmed/35477706
http://dx.doi.org/10.1038/s41467-022-29724-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046208/
https://www.ncbi.nlm.nih.gov/pubmed/35477706
http://dx.doi.org/10.1038/s41467-022-29724-4

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