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A genetically targeted sensor reveals spatial and temporal dynamics of acrosomal calcium and sperm acrosome exocytosis

Secretion of the acrosome, a single vesicle located rostrally in the head of a mammalian sperm, through a process known as “acrosome exocytosis” (AE), is essential for fertilization. However, the mechanisms leading to and regulating this complex process are controversial. In particular, poor underst...

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Detalles Bibliográficos
Autores principales: Cohen, Roy, Mukai, Chinatsu, Nelson, Jacquelyn L., Zenilman, Shoshana S., Sosnicki, Danielle M., Travis, Alexander J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046242/
https://www.ncbi.nlm.nih.gov/pubmed/35346690
http://dx.doi.org/10.1016/j.jbc.2022.101868