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Paradoxical effects of posterior intralaminar thalamic calretinin neurons on hippocampal seizure via distinct downstream circuits

Epilepsy is a circuit-level brain disorder characterized by hyperexcitatory seizures with unclear mechanisms. Here, we investigated the causal roles of calretinin (CR) neurons in the posterior intralaminar thalamic nucleus (PIL) in hippocampal seizures. Using c-fos mapping and calcium fiber photomet...

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Detalles Bibliográficos
Autores principales: Qi, Yingbei, Cheng, Heming, Lou, Qiuwen, Wang, Xia, Lai, Nanxi, Gao, Chenshu, Wu, Shuangshuang, Xu, Cenglin, Ruan, Yeping, Chen, Zhong, Wang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046245/
https://www.ncbi.nlm.nih.gov/pubmed/35494226
http://dx.doi.org/10.1016/j.isci.2022.104218