Metabolomics-based phenotypic screens for evaluation of drug synergy via direct-infusion mass spectrometry

Drugs used in combination can synergize to increase efficacy, decrease toxicity, and prevent drug resistance. While conventional high-throughput screens that rely on univariate data are incredibly valuable to identify promising drug candidates, phenotypic screening methodologies could be beneficial...

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Detalles Bibliográficos
Autores principales: Lu, Xiyuan, Hackman, G. Lavender, Saha, Achinto, Rathore, Atul Singh, Collins, Meghan, Friedman, Chelsea, Yi, S. Stephen, Matsuda, Fumio, DiGiovanni, John, Lodi, Alessia, Tiziani, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046262/
https://www.ncbi.nlm.nih.gov/pubmed/35494234
http://dx.doi.org/10.1016/j.isci.2022.104221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046262/
https://www.ncbi.nlm.nih.gov/pubmed/35494234
http://dx.doi.org/10.1016/j.isci.2022.104221

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