Cargando…
Metabolomics-based phenotypic screens for evaluation of drug synergy via direct-infusion mass spectrometry
Drugs used in combination can synergize to increase efficacy, decrease toxicity, and prevent drug resistance. While conventional high-throughput screens that rely on univariate data are incredibly valuable to identify promising drug candidates, phenotypic screening methodologies could be beneficial...
| Autores principales: | , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046262/ https://www.ncbi.nlm.nih.gov/pubmed/35494234 http://dx.doi.org/10.1016/j.isci.2022.104221 |