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Mutation in SF3B1 gene promotes formation of polyploid giant cells in Leukemia cells

Giant cells with polyploidy, termed polyploid giant cells, have been observed during normal growth, development, and pathologic states, such as solid cancer progression and resistance to therapy. Functional studies of polyploidal giant cancer cells (PGCC) provided evidence that they arise when norma...

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Detalles Bibliográficos
Autores principales: Mukherjee, Sanjay, Ali, Abdullah Mahmood, Murty, Vundavalli V., Raza, Azra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046281/
https://www.ncbi.nlm.nih.gov/pubmed/35478057
http://dx.doi.org/10.1007/s12032-022-01652-9