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Mutation in SF3B1 gene promotes formation of polyploid giant cells in Leukemia cells
Giant cells with polyploidy, termed polyploid giant cells, have been observed during normal growth, development, and pathologic states, such as solid cancer progression and resistance to therapy. Functional studies of polyploidal giant cancer cells (PGCC) provided evidence that they arise when norma...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046281/ https://www.ncbi.nlm.nih.gov/pubmed/35478057 http://dx.doi.org/10.1007/s12032-022-01652-9 |