Pyrethroid-piperonyl butoxide (PBO) nets reduce the efficacy of indoor residual spraying with pirimiphos-methyl against pyrethroid-resistant malaria vectors

Pirimiphos-methyl is a pro-insecticide requiring activation by mosquito cytochrome P450 enzymes to induce toxicity while PBO blocks activation of these enzymes in pyrethroid-resistant vector mosquitoes. PBO may thus antagonise the toxicity of pirimiphos-methyl IRS when combined with pyrethroid-PBO I...

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Detalles Bibliográficos
Autores principales: Syme, Thomas, Gbegbo, Martial, Obuobi, Dorothy, Fongnikin, Augustin, Agbevo, Abel, Todjinou, Damien, Ngufor, Corine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046380/
https://www.ncbi.nlm.nih.gov/pubmed/35478216
http://dx.doi.org/10.1038/s41598-022-10953-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046380/
https://www.ncbi.nlm.nih.gov/pubmed/35478216
http://dx.doi.org/10.1038/s41598-022-10953-y

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