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Establishment of CRFK cells for vaccine production by inactivating endogenous retrovirus with TALEN technology

Endogenous retroviruses (ERVs) are retroviral sequences present in the host genomes. Although most ERVs are inactivated, some are produced as replication-competent viruses from host cells. We previously reported that several live-attenuated vaccines for companion animals prepared using the Crandell-...

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Detalles Bibliográficos
Autores principales: Shimode, Sayumi, Sakuma, Tetsushi, Yamamoto, Takashi, Miyazawa, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046391/
https://www.ncbi.nlm.nih.gov/pubmed/35477976
http://dx.doi.org/10.1038/s41598-022-10497-1