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Establishment of CRFK cells for vaccine production by inactivating endogenous retrovirus with TALEN technology
Endogenous retroviruses (ERVs) are retroviral sequences present in the host genomes. Although most ERVs are inactivated, some are produced as replication-competent viruses from host cells. We previously reported that several live-attenuated vaccines for companion animals prepared using the Crandell-...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046391/ https://www.ncbi.nlm.nih.gov/pubmed/35477976 http://dx.doi.org/10.1038/s41598-022-10497-1 |