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Endothelial inflammation and neutrophil transmigration are modulated by extracellular matrix composition in an inflammation-on-a-chip model

Inflammatory diseases are often characterised by excessive neutrophil infiltration from the blood stream to the site of inflammation, which damages healthy tissue and prevents resolution of inflammation. Development of anti-inflammatory drugs is hindered by lack of in vitro and in vivo models which...

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Detalles Bibliográficos
Autores principales: Riddle, Rebecca B., Jennbacken, Karin, Hansson, Kenny M., Harper, Matthew T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046410/
https://www.ncbi.nlm.nih.gov/pubmed/35477984
http://dx.doi.org/10.1038/s41598-022-10849-x