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Increased fatty acid metabolism attenuates cardiac resistance to β-adrenoceptor activation via mitochondrial reactive oxygen species: A potential mechanism of hypoglycemia-induced myocardial injury in diabetes

The mechanism of severe hypoglycemia (SH)-induced cardiovascular disease in diabetes remains unknown. Our previous study found that SH inhibits cardiac function and lipid metabolism in diabetic mice. Conversely, in nondiabetic mice, SH does not induce cardiac dysfunction but promotes cardiac lipid m...

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Detalles Bibliográficos
Autores principales: Huang, Lishan, Chen, Zhou, Chen, Ruiyu, Lin, Lu, Ren, Lingjia, Zhang, Meilian, Liu, Libin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046456/
https://www.ncbi.nlm.nih.gov/pubmed/35462320
http://dx.doi.org/10.1016/j.redox.2022.102320