Capsaicin-induced depolymerization of axonal microtubules mediates analgesia for trigeminal neuropathic pain

Capsaicin is a specific agonist of transient receptor potential vanilloid 1 (TRPV1), which is enriched in nociceptors. Capsaicin not only produces acute pain but also leads to long-lasting analgesia in patients with chronic pain. Although capsaicin-induced TRPV1 and Ca(2+)/calpain-dependent ablation...

Descripción completa

Detalles Bibliográficos
Autores principales: Arora, Vipin, Li, Tingting, Kumari, Sinu, Wang, Sheng, Asgar, Jamila, Chung, Man-Kyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046530/
https://www.ncbi.nlm.nih.gov/pubmed/34724681
http://dx.doi.org/10.1097/j.pain.0000000000002529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046530/
https://www.ncbi.nlm.nih.gov/pubmed/34724681
http://dx.doi.org/10.1097/j.pain.0000000000002529

Ejemplares similares