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Capsaicin-induced depolymerization of axonal microtubules mediates analgesia for trigeminal neuropathic pain
Capsaicin is a specific agonist of transient receptor potential vanilloid 1 (TRPV1), which is enriched in nociceptors. Capsaicin not only produces acute pain but also leads to long-lasting analgesia in patients with chronic pain. Although capsaicin-induced TRPV1 and Ca(2+)/calpain-dependent ablation...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Wolters Kluwer
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046530/ https://www.ncbi.nlm.nih.gov/pubmed/34724681 http://dx.doi.org/10.1097/j.pain.0000000000002529 |