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Signaling Pathway and Small-Molecule Drug Discovery of FGFR: A Comprehensive Review

Targeted therapy is a groundbreaking innovation for cancer treatment. Among the receptor tyrosine kinases, the fibroblast growth factor receptors (FGFRs) garnered substantial attention as promising therapeutic targets due to their fundamental biological functions and frequently observed abnormality...

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Detalles Bibliográficos
Autores principales: Zheng, Jia, Zhang, Wei, Li, Linfeng, He, Yi, Wei, Yue, Dang, Yongjun, Nie, Shenyou, Guo, Zufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046545/
https://www.ncbi.nlm.nih.gov/pubmed/35494629
http://dx.doi.org/10.3389/fchem.2022.860985