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SS31 Ameliorates Oxidative Stress via the Restoration of Autophagic Flux to Protect Aged Mice From Hind Limb Ischemia

BACKGROUND: Oxidative stress and impaired autophagic flux play important roles in the development of peripheral artery disease (PAD). SS31 is considered an important antioxidant peptide and autophagy regulator. We aimed to investigate the role of SS31 in PAD myopathy and its possible mechanism both...

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Detalles Bibliográficos
Autores principales: Yang, Qiaoyun, Li, Chunqiu, Chen, Qingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046554/
https://www.ncbi.nlm.nih.gov/pubmed/35497980
http://dx.doi.org/10.3389/fcvm.2022.789331