Cargando…

ING4 Promotes Stemness Enrichment of Human Renal Cell Carcinoma Cells Through Inhibiting DUSP4 Expression to Activate the p38 MAPK/type I IFN-Stimulated Gene Signaling Pathway

Renal cell carcinoma (RCC) recurs frequently due to high metastatic spread, resulting in a high mortality. Cancer stem cells play a critical role in initiating the tumor metastasis. Inhibitor of growth 4 (ING4) is a member of the ING family, but its impact on cancer stem cells in RCC is still unknow...

Descripción completa

Detalles Bibliográficos
Autores principales: Tang, Yu, Yang, Xinyue, Wang, Qing, Huang, Haoyu, Wang, Qinzhi, Jiang, Min, Yuan, Chunluan, Huang, Yefei, Chen, Yansu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046557/
https://www.ncbi.nlm.nih.gov/pubmed/35496267
http://dx.doi.org/10.3389/fphar.2022.845097