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ZnO nanoparticles attenuate polymer-wear-particle induced inflammatory osteolysis by regulating the MEK-ERK-COX-2 axis

BACKGROUND/OBJECTIVES: Advanced thermoplastic materials, such as polyether-ether-ketone (PEEK) and highly cross-linked polyethylene (HXLPE), have been increasingly used as orthopaedic implant materials. Similar to other implants, PEEK-on-HXLPE prostheses produce debris from polymer wear that may act...

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Detalles Bibliográficos
Autores principales: Meng, Xiangchao, Zhang, Wei, Lyu, Zhuocheng, Long, Teng, Wang, You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046564/
https://www.ncbi.nlm.nih.gov/pubmed/35531425
http://dx.doi.org/10.1016/j.jot.2022.04.001