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ZnO nanoparticles attenuate polymer-wear-particle induced inflammatory osteolysis by regulating the MEK-ERK-COX-2 axis

BACKGROUND/OBJECTIVES: Advanced thermoplastic materials, such as polyether-ether-ketone (PEEK) and highly cross-linked polyethylene (HXLPE), have been increasingly used as orthopaedic implant materials. Similar to other implants, PEEK-on-HXLPE prostheses produce debris from polymer wear that may act...

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Detalles Bibliográficos
Autores principales:	Meng, Xiangchao, Zhang, Wei, Lyu, Zhuocheng, Long, Teng, Wang, You
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Chinese Speaking Orthopaedic Society 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046564/ https://www.ncbi.nlm.nih.gov/pubmed/35531425 http://dx.doi.org/10.1016/j.jot.2022.04.001

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