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Platycodon grandiflorum Triggers Antitumor Immunity by Restricting PD-1 Expression of CD8(+) T Cells in Local Tumor Microenvironment
In the tumor microenvironment (TME), the activation of programmed death-1 (PD-1)–programmed death ligand-1 (PD-L1) pathway is one of the main signals of immune escape and tumor deterioration. Clinically, the application of monoclonal antibodies slows down the progression of various malignancies and...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046572/ https://www.ncbi.nlm.nih.gov/pubmed/35496272 http://dx.doi.org/10.3389/fphar.2022.774440 |