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Single Nucleotide Variants as Proxies for HLA-A*31:01 in Native American Populations

Carbamazepine triggers dermatologic hypersensitivity reactions, associated with specific human leukocyte antigens (HLAs), especially HLA-B*15:02 and HLA-A*31:01. Previous efforts to identify single nucleotide variants (SNVs) with high predictive value as HLA proxies, revealed that rs1061235 and rs17...

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Detalles Bibliográficos
Autores principales: Fernandes, Vanessa Câmara, Pretti, Marco Antônio M., Tsuneto, Luiza Tamie, Petzl-Erler, Maria Luiza, Suarez-Kurtz, Guilherme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046591/
https://www.ncbi.nlm.nih.gov/pubmed/35496269
http://dx.doi.org/10.3389/fphar.2022.849136