TIM-3 Expression Level on AML Blasts Correlates With Presence of Core Binding Factor Translocations Rather Than Clinical Outcomes

BACKGROUND: T-cell immunoglobulin and mucin domain-containing molecule 3 (TIM-3) expresses on leukemic stem and progenitor populations of non-M3 acute myeloid leukemia (AML) as well as T lymphocytes. TIM-3 is thought to be involved in the self-renewal of leukemic stem cells and the immune escape of...

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Detalles Bibliográficos
Autores principales: Hong, Jian, Xia, Leiming, Huang, Zhenqi, Yuan, Xiaodong, Liang, Xinglin, Dai, Jifei, Wu, Zhonghui, Liang, Li, Ruan, Min, Long, Zhangbiao, Cheng, Xin, Chen, Xiaowen, Ni, Jing, Ge, Jian, Li, Qingsheng, Zeng, Qingshu, Xia, Ruixiang, Wang, Yi, Yang, Mingzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046698/
https://www.ncbi.nlm.nih.gov/pubmed/35494006
http://dx.doi.org/10.3389/fonc.2022.879471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046698/
https://www.ncbi.nlm.nih.gov/pubmed/35494006
http://dx.doi.org/10.3389/fonc.2022.879471

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