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Selective Inhibition of Histone Deacetylase Class IIa With MC1568 Ameliorates Podocyte Injury

Histone deacetylases (HDACs) inhibitors are promising therapeutic agents against proteinuric kidney diseases, here, we investigated the effect of MC1568, a selective inhibitor of HDAC class IIa, on the development and progression of nephrotic syndrome in a murine model induced by Adriamycin (ADR). I...

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Detalles Bibliográficos
Autores principales: He, Xu, Sun, Tao, Zhang, Pei, Xia, Zhengkun, Gao, Chunlin, Ren, Hongqi, Ji, Daxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9046702/
https://www.ncbi.nlm.nih.gov/pubmed/35492337
http://dx.doi.org/10.3389/fmed.2022.848938